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	Product Name:	Letrozole, Femara, LZ
	CAS No.:	112809-51-5
	Molecular Formula:	C17H11N5
	Molecular Weight:	285.30
	Assay:	98% min
	Quality Standard:	USP/BP/ISO9001
	Appearance:	White Crystalline Powder
	Supply Ability:	200-300kg/month
	Storage:	Store at 8℃-20℃, protect from moisture and light.

Specifications:

TEST ITEMS	SPECIFICATION	RESULTS
Description	White Crystalline Powder	Conforms
Melting Point	181~183 degree centigrade	181.5~183 degree centigrade
Loss On Drying	0.30%max	0.20%
Total Impurities	0.2%max	0.015%
Heavy Metals	20PPm max	<10PPm

Letrozoleis approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women. Letrozole is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.

Femara is used for the treatment of post-menopause breast cancer. Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.

For the purpose of Estrogen control during a cycle: Letrozole is the most effective aromatase inhibitor utilized to reduce levels of circulating Estrogen in the body during a cycle involving the use of aromatizable androgens (anabolic steroids that have an affinity to bind to the aromatase enzyme and undergo aromatization into Estrogen). This has been outlined previously in the introduction. Letrozole doses for this purpose cover a very wide range, and how much Letrozole is required (and how often) is also largely dependent on the doses of aromatizable anabolic steroids used, the individual’s sensitivity to aromatase inhibitors, and the rate of aromatization of the anabolic steroids used. With this being said, the general range of Letrozole doses are approximately 1.25mg – 2.5mg daily. There does exist a very large margin for adjustment and user preference when it comes to Letrozole dosages, as each individual should slowly adjust their dose depending on how they feel the body is responding. This is especially so for Letrozole, which is the most powerful and potent AI of the three. Even 1.25mg daily is too much for many anabolic steroid users, and often times the recommended dose is actually 1.25mg every other day, and often can be even less frequent especially considering the half-life of Letrozole is that of 2 – 4 days. These Letrozole doses can easily be adjusted if the user feels it is not working well enough, or if it is reducing Estrogen levels too much.